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  • Sample size issue

    Dear Stata forum members,
    I sincerely need your help! I am doing my PhD research on malaria incidence and its predictors. To execute the study, I want to recruit all age groups by assessing their baseline characteristics, and follow them for a year. My population are dynamic population where immigration and emigration is high due to the closeness of the study area to border where people influx in and move out. Therefore, what I am intending to measure is incidence density rather than a cumulative incidence. I could not get a study which followed similar design. Other studies done in my country and elsewhere recruited only febrile patients as the study population where the incidence is more likely. Therefore, my question is what is the minimum sample size (person-year) that I should follow for the study to have sufficient power and yield valid result? What is the sample size calculation formula? Can I calculate the sample size using Stata? To be frank, I tried to calculate the sample size by considering the incidence rate as proportion, which is actually not, and the sample size I got became by far less than what I expected. Help!

  • #2
    It is really hard for an outsider to get a detailed enough understanding of your design based on just one paragraph. So i am not going to try. If i were to try than the result would in all likelihood be misleading, and that is in nobody's interest .

    Instead, I am going to recommend you do the power calculations with simulation. If you are using an unusual design than standard formulas probably won't exist. Simulation is much more flexible. You can do this in Stata, see https://www.stata.com/support/faqs/s...by-simulation/
    ---------------------------------
    Maarten L. Buis
    University of Konstanz
    Department of history and sociology
    box 40
    78457 Konstanz
    Germany
    http://www.maartenbuis.nl
    ---------------------------------

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    • #3
      Thank you Buis!

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