Hello,
I would like to know how I can calculate the LD50, LD90 and LD 95 (lethal dose) for bioassays using logit regression?
I found probit regression commands, however I would like to apply the formula to STATA programming, please could someone help me?
1) For LD50 in probit and logit regression the formula is the same:
local LD50 LD50: exp (-_ b [_cons] / _ b [logdose])
2) However, for the other LD there is a change:
I found the links described at the end for the probit model as follows:
Probit: LDp = (invnormal (p) -constant) / coef
STATA command:
local ld90 LD90: exp ((invnorm (0.9) -_ b [_cons]) / _ b [logdose])
However, for the logit model the formula recommends is:
Logit: LDp = (log (p / (1-p)) - constant) / coef
How to program the above command in stata for Logit regression?
Another question is about normality: If the distribution is not normal, should I calculate LD from the Logit regression? I have read in some places that if the distribution is not parametric, logit regression should be applied for LD.
Would you have another model suggestion for calculating LD with non-normal distribution?
Thanks
LINKS:
https://www.stata.com/statalist/arch.../msg00184.html
https://www.statalist.org/forums/for...r-logit-probit
https://stats.idre.ucla.edu/other/mu...git-or-probit/
I would like to know how I can calculate the LD50, LD90 and LD 95 (lethal dose) for bioassays using logit regression?
I found probit regression commands, however I would like to apply the formula to STATA programming, please could someone help me?
1) For LD50 in probit and logit regression the formula is the same:
local LD50 LD50: exp (-_ b [_cons] / _ b [logdose])
2) However, for the other LD there is a change:
I found the links described at the end for the probit model as follows:
Probit: LDp = (invnormal (p) -constant) / coef
STATA command:
local ld90 LD90: exp ((invnorm (0.9) -_ b [_cons]) / _ b [logdose])
However, for the logit model the formula recommends is:
Logit: LDp = (log (p / (1-p)) - constant) / coef
How to program the above command in stata for Logit regression?
Another question is about normality: If the distribution is not normal, should I calculate LD from the Logit regression? I have read in some places that if the distribution is not parametric, logit regression should be applied for LD.
Would you have another model suggestion for calculating LD with non-normal distribution?
Thanks
LINKS:
https://www.stata.com/statalist/arch.../msg00184.html
https://www.statalist.org/forums/for...r-logit-probit
https://stats.idre.ucla.edu/other/mu...git-or-probit/
